Understanding Erythermalgia
Erythermalgia is a rare and often little-known disease that affects the regulation of heat and blood circulation in certain parts of the body. It causes hot flashes, redness, and burning sensations, which may be visible or felt only by the person affected. Although invisible to others, the disease is very real and affects the daily life of those who suffer from it.
How It Works
Erythermalgia results from overactivity of the peripheral nervous system, which leads to excessive dilation of blood vessels. This dysfunction causes:
- Accumulation of heat in the extremities or the face
- Intense pain during flare-ups
- Swelling (edema)
- Variations in the severity and duration of symptoms depending on the individual (which can last several hours per day)
Different Forms
- Primary erythermalgia: Often genetic, usually appearing early in life. It results from a mutation in the SCN9A gene, which encodes the sodium channel Nav1.7, causing increased excitability of pain-sensing nerve fibers.
- Secondary erythermalgia: Linked to other diseases or treatments (neurological, cardiovascular, diabetes, etc.).
Common Triggers
Although each person has their own specific triggers, flare-ups are often triggered by:
- Ambient heat (heating systems, computers, sun-exposed windows, etc.) or rapid temperature changes
- Physical activity or emotional stress
- Certain hot foods or drinks
Diagnosis
Diagnosing erythermalgia can be complex:
The condition is rare and often unfamiliar to healthcare professionals.
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One of the first causes to rule out is a myeloproliferative disorder, particularly:
platelet abnormalities, elevated hemoglobin levels, and other abnormalities on the complete blood count (CBC). -
Symptoms vary from person to person (intensity, location, frequency of flare-ups, and triggering factors).
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Specialized follow-up is essential to confirm the diagnosis and identify specific triggers.
Understanding erythermalgia, its mechanisms, and its different forms is essential to better understand the disease and to inform those around you. Even if the symptoms are invisible, knowledge and awareness can reduce isolation and encourage support.
Les Brûlures Invisibles supports patients and their loved ones by sharing this information, creating connections, and raising public awareness about this little-known disease.